Technology

Chromosomal Modifications

boite-petri-vert

 

Without scar

 

universal tool

 

Can be fully automated

molecule

 

Usable on a wide
range of bacteria

 

 

 

genome editing fully automated

COLIBELT®

Firstly developed on E. coli, BGene technology allows to modify with an accuracy up to the base the bacterial genome.

Insertion from one gene to a whole biosynthesis pathway, point mutation or deletion are possible, without leaving scars (repeats, recombination site) nor antibiotic resistance. COLIBELT® can be used on all the genotypes of E. coli and doesn’t need any particular characteristic of the strain. This technology can be fully automated, allowing the high-throughput creation of the strains.

The modifications are stable and no selection pressure is needed during the process to maintain the new characteristics of the strains.

COLIBELT® can be used as an alternative to the plasmidic expression of recombinant proteins.

genome editing on diverse bacteria

UNBELT®

Given that BGene technology is independent of genetic factors, it is usable in a wide range of bacteria.

Derived from COLIBELT® technologie and tested on both Gram positive and Gram negative bacteria, UNBELT® is the universal solution for the genetic engineering of bacterial chromosome and enables the optimization of bacteria of interest for industrial biotechnology.